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Genetic cause found for premature ovarian failure - A team led by researchers from the Spanish National Research C...


Headlines: Next Step in Live-Donor Uterus Transplant Project


If you need egg donors in UK clinics, some have spare donors. Give them a call


For oncology , how to manage or reduce the risk of premature ovarian failure:


I was prepared for the cancer treatment but not an instant menopause at 43 - Beauty Despite Cancer:


How to cope and make a decision when your doctor tells you that it's time to consider egg donation and/or surrogacy:



Researchers make first link between menopause smoking and genetic variations in white women


One month away from publishing our 'Letters to My Donor'- book. Such a beautiful piece and I cannot wait. PROUD!!


British population stats:15-24 years: female 3,986,831 & 25-54 years: female 12,807,328. Rough estimate 100,000 POI women


POI patients include ovarian activity with controlled studies showing 1.5% of women becoming pregnant, non assisted


Turner Syndrome is a chromosomal abnormality that effects growth and sexual development and causes ovarian development failure.






 Dec 25

My 5min interview Xmas Eve on being 'the childless one' at the family Xmas.

 Dec 23

Type 2 diabetes in women less than 45 triples risk of early menopause: Type 2 diabetes - the most common t...

2nd October 2013

BBC News - Early menopause: Baby born after ovaries 'reawakened'

Extract from BBC article:

"A baby has been born through a new technique to "reawaken" the ovaries of women who had a very early menopause.

Doctors in the US and Japan developed the technique to remove the ovaries, activate them in the laboratory and re-implant fragments of ovarian tissue.

The technique, reported in Proceedings of the National Academy of Sciences, has resulted in one baby being born, with another expected.

The findings were described as early, but a "potential game-changer"."

Nick Panay's feedback to Daisy members about the article. 

This gives some hope that we can use any remaining eggs in women with POI to achieve a pregnancy but it is not a technique which will reverse the menopause and it is reliant on there being some remaining follicles left to activate.

I think Jonathan Tilly's work on reactivating dormant stem cells in the ovaries of women with POI to produce new eggs has more potential to offer a solution to the problem.

Both research avenues need more development to be realistic options for the majority of women with POI.

In the meantime it is important that we start to gather good quality data (e.g. through our POI registry  to understand what causes the problem in the first place and what impact our interventions are having.




1st June 2012

A new IVF study

       A radical new study by Yale school of medicine and the university of Oxford have teamed up and have pinpointed the chromosomal make-up of human eggs. This revelation could soon allow doctors to use ‘good’ eggs during in vitro fertilisation (IVF) where-by increasing the success rate to be pregnant.

      At the moment, only a few eggs per cycle of IVF have a chance to be successful due to many eggs having the wrong number of chromo sols. The eggs are surrounded by cells called ’Cumulus cells’ that cause the egg to mature. The study found out that in these cells were a set of genes that were less active and were more prone to produce abnormal cells.

      So the bottom line is that possibly quite soon the ‘right’ eggs can be chosen to increase the success rate and produce a baby and may even bring down the cost of IVF treatment in the future.


The IVF Postcard Lottery

13th April 2012

Video news from the BBC Website


'NHS charges market rates for IVF'

The News below has been sourced from the BBC website .

A professor of fertility studies at Imperial College London has told the Independent newspaper of the "scandalous exploitation" of people trying for an IVF baby.

Professor Robert Winston explains why he thinks the market is driven by greed on the part of the clinics and desperation on the part of the would-be parents.

And Professor Alison Murdoch, head of Newcastle Fertility Centre, gives her reaction.

HFEA Updates

The News below has been sourced from:

Latest figures show rise in number of IVF treatments

New figures released today by the HFEA show that the number of IVF treatments continues to rise. They also show that the overall pregnancy and live birth rates have remained steady at a time of notable changes to clinical practice. At the same time, the overall multiple pregnancy and multiple birth rates have fallen.

These figures are contained in a new annual report from the HFEA, bringing together in an accessible way, key statistics on fertility trends in the UK.

Professor Lisa Jardine, Chair of the HFEA, said:

“The Register of all licensed treatments and outcomes for assisted reproduction held by the HFEA puts us in an unrivalled position to inform people about the performance of the fertility sector. We are now committed to publishing regular analytical reports, twice a year, one in the spring and one in the autumn. This autumn report describes general trends and figures about fertility treatments based on the latest clinic data we hold, data for 2010 and in some cases 2009.”

Key figures include:

  • In 2010, 45,264 women received a total of 57,652 IVF or ICSI treatments, an increase of 5.9% on the number of cycles in 2009.
  • A total of 12,386 pregnancies were reported as a result of fresh IVF or ICSI treatment which started in 2009 whilst 13,015 pregnancies followed treatment started in 2010. This translates to a pregnancy rate (per embryo transfer) of one third (33.4%) – a figure which remained constant over both years.  
  • The majority of women who received IVF treatment in 2010 were aged 37 years or under, with that age group making up almost two thirds of all those treated. The average age of women undergoing IVF treatment was 35.
  • London has the largest number of licensed fertility clinics in the UK, with 15 clinics treating nearly 14,000 women in 2010.
  • Following the trend for increasing IVF in general, the number of women receiving treatment with donated eggs and sperm each year has risen between 2009 and 2010.
  • The number of donor insemination cycles rose very slightly in the last year, with 3,878 cycles in 2010 compared with 3,847 in 2009 (an increase of 0.8%).  The live birth rate for DI cycles was 11%.
  • Meanwhile, 2010 saw an increase in the number of women receiving IVF treatment with donor eggs or sperm. In 2009 there were 1,615 cycles of IVF treatment with donated sperm resulting in 585 babies being born; in 2010, this had increased to 1,963 cycles (a 21.5% increase). In 2009, there were 1,254 cycles of IVF with donated eggs, resulting in 550 babies being born; in 2010, this had increased to 1,320 cycles (a 5.3% increase).
  • There has also been good progress made in the last year in reducing multiple births following IVF, particularly in the youngest age group. In 2009, just under a quarter (24.9%) of live births in those aged 18 – 34 years were multiple ones. This compares with 29.4% in 2008. 
  • Only a minority of IVF treatment cycles in 2010 were funded by the NHS, with 40% being funded by them and 60% being funded by the patients themselves. This compares with 62% being privately funded in 2009.

Donor statistics

About these figures

  • The information that we publish on our website is subject to constant verification as individual centres notify us of amendments. It may therefore vary slightly with each update. These figures represent a snap shot of data provided to us by licensed centres at a particular time. Before publication, we perform a preliminary validation process on the data, and ask the centres to confirm its accuracy for which they remain responsible.
  • The donor numbers published here will be updated annually.

Donor numbers

  • The donor numbers were extracted from the HFEA's data warehouse containing Register data as at 14/02/2009.

Donor treatment and births

  • The number of treatments and patients using donor eggs, sperm and embryos includes fresh and frozen IVF cycles, stimulated and unstimulated. IVF treatments involving ICSI are not included, except where shown for comparison.
  • This treatment and patient data was extracted from the HFEA's data warehouse containing Register data as at 08/07/2009.